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  • 產(chǎn)品名稱： Succinylated Lysine Rabbit Polyclonal Antibody
  • 產(chǎn)品貨號： CS3089
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購： 2398
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 100μl 1ml
  • 產(chǎn)品信息
  • 如何訂購
    Attribute
    Rabbit Polyclonal Antibody 
    Isotype
    IgG
    Purity
    Antigen Affinity Purification 
    Application
    WB, IP, ELISA
    Reactivity
    Succinylated Protein 
    Immunogen
    Succinylated BSA
    Buffer
    PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 
    Storage
    Store at -20℃. Do not aliquot 
    Recommended Dilution
    WB: 1:1000-2000  IP: 1:5000-10000 
    Background
    Succinylation   is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H)   is added to a lysine residue of a protein molecule. This modification is   found in many proteins, including histones. The potential role of   succinylation is under investigation, but as addition of succinyl group   changes lysine's charge from +1 to ?1 (at physiological pH) and introduces a   relatively large structural moiety (100 Da), bigger than acetylation (42 Da)   or methylation (14 Da), it is expected to lead to more significant changes in   protein structure and function. By analogy to acetylation, it has been   suggested that succinyl-CoA is the cofactor of enzyme-mediated lysine   succinylation.
    Note
    For research use only .