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  • 產品名稱： Recombinant Human BMPR1A protein
  • 產品貨號： CSP01668
  • 貨期： 現貨
  • 價格與訂購： 1800
  • 數量：
    庫存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產品信息
  • 如何訂購
    概述（Summary）
    英文全稱
    Recombinant Human BMPR1A protein
    純度（Purity）
    >90% as determined by SDS-PAGE
    內毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構建（Construction）
    A DNA sequence encoding the human BMPR1A (Gln24-Arg152) was fused with His tag
    Accession #
    P36894
    表達宿主（Host）
    E.coli
    種屬（Species）
    Homo sapiens (Human)
    預測分子量（Predicted Molecular Mass）
    15.57 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景（Background）
    背景介紹
    Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
     
    分子別名（Alternative Names）
    Bone morphogenetic protein receptor type-1A,Short name:BMP type-1A receptor,Short name:BMPR-1A,Activin receptor-like kinase 3,Short name:ALK-3,Serine/threonine-protein kinase receptor R5,Short name:SKR5,CD_antigen: CD292.
    Note
    For research use only .