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  • 產品名稱： Recombinant Human LYPLA2 protein
  • 產品貨號： CSP01448
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 1800
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產品信息
  • 如何訂購
    概述（Summary）
    英文全稱
    Recombinant Human LYPLA2 protein
    純度（Purity）
    >90% as determined by SDS-PAGE
    內毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構建（Construction）
    A DNA sequence encoding the human LYPLA2 (Met1-Thr196) was fused with His tag
    Accession #
    O95372
    表達宿主（Host）
    E.coli
    種屬（Species）
    Homo sapiens (Human)
    預測分子量（Predicted Molecular Mass）
    21.69 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景（Background）
    背景介紹
    Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity, and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipid hydrolyzing enzymes. The serum activity of APT-1 may play an important role in determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. APT-2/LYPLA2 is expressed both in CHO-K1 and HeLa cells and its overexpression increased the deacylation rate of single acylated GAP-43 and affected the steady-state localization of diacylated GAP-43 and H-Ras. Thus, the results demonstrate that APT-2/LYPLA2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution.
    分子別名（Alternative Names）
    APT-2 Protein, Human; APT2 Protein, Human; DJ886K2.4 Protein, Human
    Note
    For research use only .