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  • 產(chǎn)品名稱： Recombinant Human FABP3 protein
  • 產(chǎn)品貨號： CSP01213
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購： 1800
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購
    概述（Summary）
    英文全稱
    Recombinant Human FABP3 protein
    純度（Purity）
    >90% as determined by SDS-PAGE
    內(nèi)毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構(gòu)建（Construction）
    A DNA sequence encoding the human FABP3 (Met1-Ala133) was fused with His tag
    Accession #
    P05413
    表達(dá)宿主（Host）
    E.coli
    種屬（Species）
    Homo sapiens (Human)
    預(yù)測分子量（Predicted Molecular Mass）
    16.24 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景（Background）
    背景介紹
    Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular signaling and gene transcription. Previously FABP3 was involved in apoptosis-associated congenital cardiac malformations. FABP3 knockdown exhibited significant toxic effects on cardiac development and mitochondrial function, which may be responsible for the knockdown of FABP3-induced apoptosis. FABP3 as a candidate gene underlying the etiology of congenital heart defects. Overexpression of FABP3 inhibited cell growth and proliferation via negative regulation of the cell cycle and down-regulation of cell growth factors, but enhances cell survival in hypoxic or ischemic conditions. FABPs are known to be carrier proteins for transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus, where these lipids are released to a group of nuclear receptors such as peroxisome proliferator-activated receptors (PPARs).
    分子別名（Alternative Names）
    Fatty acid-binding protein, heart,Fatty acid-binding protein 3,Heart-type fatty acid-binding protein,H-FABP,Mammary-derived growth inhibitor,MDGI,Muscle fatty acid-binding protein,M-FABP.
    Note
    For research use only .