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  • 產(chǎn)品名稱(chēng)： Recombinant Human MOG protein
  • 產(chǎn)品貨號(hào)： CSP01166
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 1800
  • 數(shù)量：
    庫(kù)存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    概述（Summary）
    英文全稱(chēng)
    Recombinant Human MOG protein
    純度（Purity）
    >90% as determined by SDS-PAGE
    內(nèi)毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構(gòu)建（Construction）
    A DNA sequence encoding the human MOG (Gly30-Tyr149) was fused with His tag
    Accession #
    Q16653
    表達(dá)宿主（Host）
    E.coli
    種屬（Species）
    Homo sapiens (Human)
    預(yù)測(cè)分子量（Predicted Molecular Mass）
    15.39 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景（Background）
    背景介紹
    Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately .1% total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.
    分子別名（Alternative Names）
    Myelin-oligodendrocyte glycoprotein.
    Note
    For research use only .