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產品名稱： Research Grade Placulumab ( 普拉魯單抗 )
產品貨號： CSD00297
貨期： 現(xiàn)貨
價格與訂購： 2480
數(shù)量：

庫存： 100
規(guī)格： 100μg

產品信息
如何訂購

貨號（Catalog No.）

CSD00297

通用名INN

Placulumab

純度(Purity)

>95%

濃度( Concentration)

1mg/ml

Formulation

PBS buffer PH7.5

Source

CHO cells

內毒素(Endotoxin level)

Please contact with the lab for this information.

產品描述(Description)

Placulumab has been used in trials studying the treatment of Rheumatoid Arthritis.

別名(Alternative names)

ART621,CEP-37247,PN0621

靶點;物種(Specificity target name;species)

TNFSF2/TNF-alpha/TNFA[Homo sapiens]

活性研究（體外/體內研究）(Activity in vitro)

Adalimumab (anti-TNF-alpha) blocks the interaction of TNF with the p55 and p75 cell surface TNF receptors, thereby neutralising the activity of this cytokine. Through its anti-TNF actions, adalimumab reduces concentrations of matrix metalloproteases (MMP-1 and -3) and other markers of cartilage and synovium turnover, reduces of matrix metalloproteases (MMP-1 and -3) and other markers of cartilage and synovium turnover, and reduces concentrations of acute phase reactants of inflammation (C-reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) and serum cytokines (IL-1β mRNA, IL-1 receptor antagonist, IL-6).

種類(Species)

Homo sapiens

受體鑒定(Receptor identification)

[V-kappa]2-Fc

CAS

945781-29-3

存儲條件(Storage)

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Store at +4°C short term (1-2 weeks).

Store at -20 °C 12 months.

Store at -80°C long term.

Note