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  • 產(chǎn)品名稱： Research Grade Daratumumab ( 達(dá)妥木單抗 )
  • 產(chǎn)品貨號(hào)： CSD00199
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購： 2480
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 100μg
  • 產(chǎn)品信息
  • 如何訂購
    貨號(hào)（Catalog No.）
    CSD00199
    通用名INN
    Daratumumab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    產(chǎn)品描述(Description)
    Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells.
    別名(Alternative names)
    HuMax-CD38
    靶點(diǎn);物種(Specificity target name;species)
    CD38[Homo sapiens]
    活性研究（體外/體內(nèi)研究）(Activity in vitro)
    Daratumumab was studied in a series of in vitro assays and was found to induce CDC in freshly isolated MM cells obtained from the bone marrow of 13 previously untreated or relapsed MM patients. Furthermore, daratumumab triggered antibody-dependent cell-mediated cytotoxicity (ADCC) in CD38-expressing MM cell lines in peripheral blood mononuclear cells (PBMCs) enriched for NK cells, as well as in patient MM cells in the presence of both autologous and allogeneic effector cells.
    種類(Species)
    Homo sapiens
    受體鑒定(Receptor identification)
    IgG1-kappa
    分子量(MV)
    148000.00 Da
    CAS
    945721-28-8
    存儲(chǔ)條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .